Cannabidiol (CBD) is a substance contained in the cannabis plant that is commonly used to treat chronic pain and anxiety problems. CBD is not euphoric or intoxicating like tetrahydrocannabinol (THC). CBD’s efficacy to treat seizures is still being researched. CBD is now licensed for the treatment of epilepsy and tuberous sclerosis complex seizures. CBD may potentially be an effective therapy for other kinds of epilepsy, according to some early research.
How does CBD oil for epilepsy work?
It is stillunclear how CBD helps prevent epilepsy. The endocannabinoid system is a network of neurotransmitters and receptors in your body. This system is supposed to assist control bodily activities such as food, sleep, and pain, as well as immune system response. CBD oil for epilepsy is hypothesized to influence these processes through interacting with receptors in your endocannabinoid system.
According to animal studies, CBD’s anti-seizure actions may result from lowering neuron excitability by acting on two types of receptors known as GPR55 and TRPV1 receptors. The Food and Medicine Administration (FDA) has now authorized the prescription drug CBD Epidolex to treat Lennox-Gastaut and Dravet syndromes, two uncommon types of epilepsy. It is also authorized by the FDA for the treatment of seizures induced by the genetic condition tuberous sclerosis complex.
Research regarding Children with epilepsy and CBD
CBD may aid children with epilepsy whose symptoms may not respond well to standard therapy. The FDA, for example, has authorized Epidiolex for persons over the age of who have Lennox-Gastaut and Dravet syndromes. According to a review published in the Journal of Clinical Neurophysiology, CBD, whether solo or as part of a CBD-enriched herbal extract, can reduce relapse rates in children with treatment-resistant epilepsy.
According to a second analysis published in Epilepsia, while data shows that CBD may lessen seizures in children with drug-resistant epilepsy, similar findings may not apply to other cannabis chemicals in the plant. CBD, according to researchers, is the only acknowledged chemical with these qualities. In terms of long-term efficacy, CBD may not be appropriate for all children. According to a research published in CNS Drugs, CBD was beneficial in around 27% of children with treatment-resistant epilepsy during a 4-year period.
What is the best way to use CBD oil for epilepsy?
When utilizing CBD oil for epilepsy, it is critical to consult with a doctor. Your doctor can advise you on if CBD will interact with any of your existing drugs. According to research, some people experience more seizures after using CBD. Your doctor can assist you in monitoring your seizure frequency and determining whether CBD is appropriate for you.
Epidolex’s suggested beginning dosage is 2.5 mg/kg twice day. Following a week, the dosage can be raised to 5 mg/kg twice day. It can be raised to a maximum of 10 mg/kg twice per day based on an individual’s reaction and tolerability. If you’re using CBD oil for epilepsy, don’t quit suddenly since it may cause an increase in seizure activity.